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White House to fix ‘formatting errors’ in RFK Jr. ‘MAHA Report’: The White House on Thursday said it will fix errors in its “Make America Healthy Again,” or MAHA, report after a news outlet’s investigation found that it cited sources that don’t exist. The report, released last week to much fanfare by the administration, cited hundreds of studies to purportedly find the root causes of chronic diseases. Health and Human Services Secretary Robert F. Kennedy Jr. called the report a “milestone.”
But an examination by the news organization NOTUS found that some of those studies did not actually exist.  

About Covid-19

Contradicting RFK Jr., CDC keeps recommending covid vaccine for kids: Coronavirus vaccines are still recommended for healthy children if their doctors approve, according to updated immunization schedules published late Thursday by the Centers for Disease Control and Prevention, contradicting Health and Human Services Secretary Robert F. Kennedy Jr.’s announcement earlier this week

Prior COVID vaccination produces immune response against new SARS-CoV-2 strains, study finds: The findings are promising and suggest that, despite a drop in antibodies for mutated parts of the virus, vaccination offers ongoing protection from severe disease.

About health insurance/insurers

EMPLOYER HEALTH PLAN PERFORMANCE GAP EXPANDS, SAYS J.D. POWER:  KEY TAKEAWAYS:
The latest results from J.D. Power show a growing gap between high- and low- performing health plans in the U.S.
The best performers — regional, Blue Cross Blue Shield, and provider-sponsored plans — are getting better while the worst performers — the large national carriers — are getting worse.
Member experience has become a competitive differentiator — something for all carriers to keep in mind as employers make benefit decisions. 

About hospitals and healthcare systems

13 health systems with credit rating upgrades FYI

4 new health systems launched in 2025 FYI

About the public’s health

Projected Outcomes of Removing Fluoride From US Public Water Systems:This cost-effectiveness analysis using data for 8484 children (mean age, 9.6 years) from the US National Health and Nutrition Examination Survey for 2013 to 2016 found that elimination of fluoride would be associated with an increase in tooth decay of 7.5 percentage points and cost approximately $9.8 billion over 5 years.  

About healthcare personnel

Physician Practice Benchmark Survey Among the findings: Forty-two percent of physicians were in private practice in 2024, an 18 percentage point drop since 2012 (our first year of the Benchmark Survey)…An additional 7.7 percent of physicians (data not shown) indicated that they or another physician had an ownership stake in their practice but identified their practice as owned by a hospital, private equity group, or insurer…

Today's News and Commentary

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About Covid-19

A new variant of COVID-19 may be driving up cases in some parts of the world, WHO says: COVID-19 cases are rising again as a new variant begins to circulate in some parts of the world. The World Health Organization said Wednesday the rise in cases is primarily in the eastern Mediterranean, Southeast Asia and western Pacific regions.
Airport screening in the United States has detected the new variant in travelers arriving from those regions to destinations in California, Washington state, Virginia and New York.
The new variant is called NB.1.8.1. It arrives as the United States’ official stance on COVID-19 vaccination is changing. On Tuesday, Health Secretary Robert F. Kennedy Jr. announced that COVID-19 shots are no longer recommended for healthy children and pregnant women — a move immediately questioned by several public health experts.

About health insurance/insurers

States providing Medicaid coverage to undocumented immigrants could face $92B in penalties: States that extend Medicaid coverage to individuals without legal status will receive fewer federal Medicaid dollars if budget legislation passed by the House of Representatives is finalized, according to KFF
The legislation would reduce federal Medicaid funding matches to 80% instead of 90% for states that extend coverage to individuals regardless of immigration status. Currently, 14 states and the District of Columbia provide Medicaid coverage to undocumented children, and seven states extend coverage to undocumented adults. 

The top-ranked commercial health plans for member experience | 2025 FYI

Healthcare billing fraud: 10 recent cases  Note not only the type of fraud but that they involved federal programs.

About pharma

7 top pharmas posted revenue declines in Q1. The common thread? All are US firms FYI

About the public’s health

Moderna reports early immunogenicity data for bird flu jab as HHS pulls funding: Moderna is facing another setback from the vaccine-sceptical Trump administration, with the company disclosing Wednesday that the Department of Health and Human Services (HHS) has cancelled over $760 million in funding to develop vaccines for pre-pandemic influenzas — including bird flu. 
"After a rigorous review, we concluded that continued investment in Moderna’s H5N1 mRNA vaccine was not scientifically or ethically justifiable," remarked HHS Communications Director Andrew Nixon. "The reality is that mRNA technology remains under-tested, and we are not going to spend taxpayer dollars repeating the mistakes of the last administration, which concealed legitimate safety concerns from the public."
The announcement came in conjunction with an interim data readout from Moderna's 300-person Phase I/II trial of its H5 avian influenza vaccine, mRNA-1018. 
More than 97% of participants who received two doses of the experimental vaccine had haemagglutination inhibition (HAI) antibody titres ≥1:40 — the level considered to be protective — at three weeks after the second vaccination. About 2% of individuals had protective levels of HAI antibodies at baseline. 
In addition, mRNA-1018 was generally well-tolerated, with most adverse reactions being either Grade 1 or 2, and no dose-limiting tolerability concerns. Moderna plans to present additional data at an upcoming scientific meeting.   
Comment: Another HHS political pronouncement masquerading as scientifically reasoned.

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RFK Jr. threatens to bar government scientists from publishing in leading medical journals: HHS Secretary Robert F. Kennedy Jr. threatened to stop government scientists from publishing their work in major medical journals on a podcast Tuesday as part of his escalating war on institutions he says are influenced by pharmaceutical companies.
Speaking on the “Ultimate Human” podcast, Kennedy said the New England Journal of Medicine, the Journal of the American Medical Association and The Lancet, three of the most influential medical journals in the world, were “corrupt” and publish studies funded and approved by pharmaceutical companies. 
“Unless those journals change dramatically, we are going to stop NIH scientists from publishing in them and we’re going to create our own journals in-house,” he said, referring to the National Institutes of Health, an HHS agency that is the world’s largest funder of health research.
Comment: While these Journals have very rigorous peer review and conflict-of-interest vetting processes, I wonder if the articles in RFK, Jr’s proposed journal would have the same scrutiny. My prediction: Academic articles derived from federally funded research will be prohibited from publishing in any but Kennedy’s journal. Watch for First Amendment lawsuits.

About health insurance/insurers

Blue Cross Blue Shield plans reverse course on GLP-1 coverage: Several Blue Cross Blue Shield (BCBS) plans are reversing their course on covering GLP-1 medications, particularly for weight loss, citing high costs and the novelty of these drugs. Some plans, like Blue Cross Blue Shield of Michigan and Blue Cross and Blue Shield of Massachusetts, are discontinuing coverage for GLP-1s used solely for weight loss, starting in 2026. However, they will continue to cover these medications when prescribed for Type 2 diabetes or other approved medical conditions. 

About hospitals and healthcare systems

61 health systems ranked by total assets FYI

About pharma

Lilly snaps up non-opioid pain startup SiteOne for up to $1B: Eyeing an expansion of its pain portfolio, Eli Lilly entered the sodium channel inhibitor space on Tuesday through the acquisition of SiteOne Therapeutics. While the upfront amount was not disclosed, the total deal is valued at up to $1 billion, including regulatory and commercial milestones. 
The takeout comes on the heels of a megaround for SiteOne — and the first FDA approval for a non-opioid pain medication in more than two decades.
 

About the public’s health

HHS cancels nearly $600 million Moderna contract on vaccines for flu pandemics: The Department of Health and Human Services has notified Moderna that it is canceling a nearly $600 million contract with the company to develop, test, and license vaccines for flu strains that could trigger future pandemics, including the dangerous H5N1 bird flu virus. 

Time to Treatment Initiation [TTI] for the 30 Most Prevalent Cancer Types: Trends and Predictors of Change: The proportion of patients diagnosed with new stage I disease increased by 52.2% from 2004 (28.4%, n = 78,732) to 2015 (43.2%, n = 256,150). All other stages decreased in percent incidence. There was a 100.0% increase in median TTI for stage I patients from 2004 to 2015 (14-28 days). Cancer stage was the most important predictor of change in TTI for 16 cancer types (P < .001 for all 16).

About healthcare personnel

New Survey Shows Physician Appointment Wait Times Surge: 19% Since 2022, 48% Since 2004: The time required to schedule a physician appointment in 15 major metropolitan areas has increased by 19% since 2022 and by 48% since 2004…
 The 2025 Survey of Physician Appointment Wait Times reveals that it now takes an average of 31 days to schedule a physician appointment in 15 of the largest metropolitan areas in the United States. This is an increase from 26 days in 2022, the last year the survey was conducted, and from 21 days in 2004, the first year the survey was conducted.
"Average physician appointment wait times are the longest they have been since we began conducting the survey in 2004," said Leah Grant, president of AMN Healthcare's Physician Solutions division (formerly known as Merritt Hawkins). "Longer physician appointment wait times are a significant indicator that the nation is experiencing a growing shortage of physicians." 
Comment: See the article for specialty-specific data.

About health technology

GTCR sells Antylia Scientific for $1.34 billion:  Private equity’s GTCR is selling Vernon Hills-based Antylia Scientific, a maker of molecular diagnostic reagents, specialty chemicals, and water- and air-quality testing equipment, to Brookfield Asset Management and CDPQ in a $1.34 billion deal.
The sale marks the second deal of more than $1 billion for one of GTCR’s portfolio companies this month, following its similar-sized saleof insurance technology firm Itel.  

Gene therapy trial reports patient death, FDA enacts clinical hold: Rocket Pharmaceuticals said the patient experienced “clinical complications related to a capillary leak syndrome,” a rare disorder in which fluids escape blood vessels and enter surrounding tissue. The company voluntarily paused further dosing in the 12-person trial before the FDA placed a clinical hold on May 23.
Since then, the patient died after an acute systemic infection, according to a May 27 news release from the company.

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About Covid-19

Why are more than 300 people in the US still dying from COVID every week?: The experts said there are a few reasons why people might still be dying from the virus, including low vaccination uptake, waning immunity and not enough people accessing treatments.
In a related story, check out this post from HHS stating the latest vaccination policy.  

About hospitals and healthcare systems

The only 24 hospitals to earn Magnet’s top honor  FYI

About pharma

Prices for new US drugs doubled in 4 years as focus on rare disease grows: U.S. prices for newly-launched pharmaceuticals more than doubled last year compared to 2021, as companies leveraged scientific advances to develop more therapies for rare diseases, which typically command high prices, a Reuters analysis found.
The median annual list price for a new drug was over $370,000 in 2024, according to the Reuters survey of 45 medicines.
In 2021, the median price was $180,000 for the 30 drugs first marketed through mid-July, according to a study published in JAMA based on the same criteria. The median launch price was $300,000 in 2023 and $222,000 in 2022. 

Assessing US Food and Drug Administration Guidance Practices in Drug Development FYI

About the public’s health

PATIENT ACCESS TRENDS: INSIGHTS FROM EXPERIAN’S RECENT RCM SURVEY: There is some discrepancy between providers and patients when it comes to patient access, according to a new report from Experian Health. And that could impact revenue cycle management.
Just over one-third of providers surveyed said patient access has improved, but only 16% of patients agreed. Conversely, only 15% of patient respondents said that patient access was worse in 2024 – the lowest amount since Experian began asking the question in 2022. 

About healthcare IT

OpenAI’s $6.5 Billion Hardware Acquisition And HealthBench Work Will Accelerate Healthcare AI Capabilities: OpenAI, the famed company behind ChatGPT, released HealthBench, a new standard to measure AI outputs specifically for healthcare use cases. The company indicates that creation of the standard involved the partnership of 262 physicians across 60 countries to develop 5,000 conversations with customized “rubrics” for each to determine the efficacy and quality of responses from models. 

Today's News and Commentary

HealthcareInsights.MD will resume on Tuesday, May 27 in consideration of Memorial Day.

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White House unveils ‘MAHA’ report: 10 takeaways:The White House’s Make America Healthy Again Commission published its anticipated report on childhood chronic disease May 22. 
Comment: Some true statements and some false (like vaccine skepticism). The report did not have any recommendations, which supposedly are forthcoming.

Proposed cuts to SAMHSA, AHRQ could further stress primary care system: The specific cuts to some of the major, more easily recognizable agencies include:

  • $17.965 billion cut to the NIH;

  • $3.588 billion cut to the CDC;

  • $1.732 billion cut to the Health Resources and Services Administration (HRSA); and

  • $674 million cut to CMS.

About health insurance/insurers

UnitedHealth’s former CEO resigns from board of directors: UnitedHealth Group’s former CEO Andrew Witty has resigned from the company’s board of directors, effective immediately. 
Mr. Witty will not stand for re-election as a director during the company’s annual shareholder meeting scheduled for June 2, the company said in regulatory documents filed May 21.

Claim denials grew as prior authorization rejections fell in 2024: Health insurance companies initially declined to pay more than one dollar for every $10 providers submitted in claims last year, an increase from 2023. 

About hospitals and healthcare systems

CMS updates hospital price transparency guidance following executive order: In the updated guidance, CMS said hospitals must display payer-specific standard charges as dollar amounts in their machine-readable files (MRFs) whenever calculable. This includes the amount negotiated for the item or service, the base rate negotiated for a service package and a dollar amount if the standard charge is based on a percentage of a known fee schedule.
CMS also said hospitals should discontinue encoding “999999999” (nine 9s) in the estimated allowed amount data element within the MRF, and instead encode an actual dollar amount. 

About pharma

Unlike CVS, Walgreens Interested In Rite Aid Patient Files, Not Stores: Walgreens confirmed its only buying prescription files and not brick and mortar stores among the pharmacy assets being sold across the U.S. by Rite Aid.
A U.S. Bankruptcy Court in New Jersey approved the sale of pharmacy assets from more than 800 Rite Aid stores to CVS Health, Walgreens as well as grocery store chains including Kroger and Albertsons.
But CVS appears to be the only major drugstore chain interested in brick-and-mortar stores, confirming plans to buy 64 Rite Aid stores in the pacific northwest U.S. CVS is also purchasing prescription files of 625 Rite Aid pharmacies across 15 states in markets already served by CVS pharmacies, the company said. 

About the public’s health

‘World-first’ gonorrhoea vaccine to be rolled out in England and Wales: A vaccine for gonorrhoea will be rolled out in England and Wales as part of a world-first programme, officials have announced.
The move, hailed as a “landmark moment for sexual health”, will aim to tackle rising levels of the sexually transmitted infection (STI).

FDA vaccine panel recommends retaining JN.1 COVID-19 variant for new season jabs: The FDA’s vaccine advisory panel unanimously recommended maintaining JN.1 lineage variants for the forthcoming respiratory virus season's COVID-19 vaccines.
The agency’s Vaccines and Related Biological Products Advisory Committee (VRBPAC), which convened on Thursday, delivered its recommendation following an assessment of current variant circulation patterns and nonclinical vaccine performance data.  

Priority Health Conditions and Global Life Expectancy Disparities: This cross-sectional study suggests that a limited number of causes account for most life expectancy disparities. Together with current information on risk factors, interventions, and morbidity not yet reflected in life expectancy, the varying contributions of these causes to gaps in life expectancy can help focus health policy and guide interventions to reduce risk factors and treat conditions.
Comment: See the graphics for more detailed information. Conditions’ importance vary by region.

Hold My Beer: The Linkage between Municipal Water and Brewing Location on PFAS in Popular Beverages: PFAS were detected in most beers, particularly from smaller scale breweries located near drinking water sources with known PFAS. Perfluorosulfonic acids, particularly PFOS, were frequently detected, with PFOA or PFOS above U.S. EPA’s Maximum Contaminant Limits in some beers. There was also a county–level correlation between the total PFAS, PFOA, and PFBS concentrations in drinking water and beers. Given that approximately 18% of U.S. breweries are located within zip codes with detectable PFAS in municipal drinking water, our findings, which link PFAS in beer to the brewery water source, are intended to help inform data-driven policies on PFAS in beverages for governmental agencies, provide insights for brewers and water utilities on treatment needs, and support informed decision-making for consumers.
Comment: Read the article for assessments of where these contaminants are high.

About healthcare IT

Health system kickback scheme involves Epic EHR: An alleged kickback scheme that a California health system settled for $31.5 million involved steering physicians to use its Epic EHR. 

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House passes Trump’s agenda bill: 6 things to know  A good summary of the Bill’s health provisions.

GOP budget bill would slash Medicare funding by $490B: CBO: According to a May 20 report from the nonpartisan Congressional Budget Office, the legislation is projected to add $2.3 trillion to the national debt, triggering automatic budget cuts under federal law.
The CBO estimates that an average annual increase of $230 billion in the deficit will occur each year under the legislation, resulting in a need to reduce spending by that amount annually. The first round of sequestration could take place in 2026.
Medicare spending is limited to a 4% reduction each year, which would amount to $45 billion in cuts for fiscal year 2026. Although Medicare is capped at these 4% reductions, the rest of the federal budget would face even larger cuts. Some programs, such as Social Security and low-income assistance programs, are exempt from sequestration, leaving other federal programs to shoulder the remaining cuts. 

About health insurance/insurers

CMS plans ‘aggressive’ Medicare Advantage audits: MS will audit every Medicare Advantage plan for potential overpayments annually, in what the agency called an “aggressive” plan to step up oversight. According to a May 21 news release, the agency plans to audit each of the more than 500 MA plans each year. Currently, the agency audits around 60 plans each year. 

About pharma

Moderna 'voluntarily' pulls FDA application for combo flu/COVID-19 vaccine: Moderna said Wednesday that it has voluntarily withdrawn an application with the FDA seeking approval of its combination influenza/COVID-19 vaccine mRNA-1083 for adults aged 50 years and older. While the submission had a target review date in November, the company recently pushed back the mRNA-based jab's timeline after the FDA said that it required Phase III flu efficacy data.

Judge approves Rite Aid assets sale: On May 21, a federal judge approved Rite Aid’s bankruptcy plan to close stores and sell most of its pharmacy assets to other national chains, according to court documents reviewed by Becker’s
CVS, Walgreens, and grocery store chains Albertsons, Kroger, Giant Eagle and others have entered into separate transactions to buy Rite Aid’s assets, including prescription services and 810 of its 1,240 pharmacy locations.  

GoodRx to directly contract with independent pharmacies: In June, GoodRx will provide a cost-plus model offering to independent community pharmacies through direct contracts, the company said May 22. 
Dubbed GoodRx Community Link, it will allow locally owned and operated pharmacies to contract with its integrated savings program. The program compares a medication’s copay with GoodRx’s discount price to offer the lowest available price.

2025 Prescription Drug Expenditure Projections for Health System Leaders: The overall prescription drug spending in the United States in 2025 is predicted to rise between 9% and 11% higher than 2024 spending, which totaled $806 billion, according to a recently published paper on national trends in prescription drug expenditures and projections for 2025 in the American Journal of Health-System Pharmacy.
Drug spending at clinics in 2025, the paper predicts, will likely be higher than spending at hospitals, with an 11.0% to 13.0% increase. Lead author Eric Tichy, Pharm.D., M.B.A., vice chair of pharmacy formulary at Mayo Clinic Health System, explained there has been an effort to move more care into the outpatient setting. Additionally, innovation is allowing more drugs to be approved that can be administered in the ambulatory setting.

About the public’s health

Nutritional Content of Ready-to-Eat Breakfast Cereals Marketed to Children: Analysis of newly launched children’s RTE cereals from 2010 to 2023 revealed concerning nutritional shifts: notable increases in fat, sodium, and sugar alongside decreases in protein and fiber. Children’s cereals contain high levels of added sugar, with a single serving exceeding 45% of the American Heart Association’s daily recommended limit for children. These trends suggest a potential prioritization of taste over nutritional quality in product development, contributing to childhood obesity and long-term cardiovascular health risks.

U.S. Global Health Country-Level Funding TrackerA very interesting chart of where the U.S. spends its global health dollars (by country) and on what programs.


Exclusive: Opioid use disorder costs almost $700K per case: State of play:
Opioid use disorder — defined as frequent opioid use and unsuccessful efforts to quit — is estimated to affect more than 6 million people in the United States.

  • The cumulative economic burden on patients, including years of life lost and reduced quality of life, exceeded $3 trillion in 2024, Avalere estimated.

  • Private businesses absorbed more than $467 billion in costs from lost productivity and health insurance costs while the federal government bore about $118 billion in Medicare and other federal insurance costs, lost taxes and criminal justice expenses.

  • It cost state and local governments more than $94 billion, with about $42 billion of that going toward criminal justice costs.

  • The Trump administration in March released its own analysis that estimated illicit opioids cost the U.S. about $2.7 trillion in 2023.  

About healthcare IT

In lawsuit over teen’s death, judge rejects arguments that AI chatbots have free speech rights: A federal judge on Wednesday rejected arguments made by an artificial intelligence company that its chatbots are protected by the First Amendment — at least for now. The developers behind Character.AI are seeking to dismiss a lawsuit alleging the company’s chatbots pushed a teenage boy to kill himself.
The judge’s order will allow the wrongful death lawsuit to proceed, in what legal experts say is among the latest constitutional tests of artificial intelligence.

About healthcare personnel

61% of nurses plan job change within 1 year: Report: Within the next 12 months, 61% of more than 12,000 nurses surveyed by AMN Healthcare said they plan to leave their current employer, switch departments, retire, return to school, or work part-time, per diem or in a virtual role. 
High levels of burnout, stress and dissatisfaction continue to foment workforce instability. The National Council of State Boards of Nursing’s biennial 2024 National Workforce Study, which surveyed more than 800,000 U.S. nurses, found that 40% of RNs plan to exit the field by 2029. 

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About health insurance/insurers

In a significant change, House GOP tax cut bill would start Medicaid work requirements next year: The latest draft of the House tax cut bill calls for starting Medicaid work requirements next year, up from 2029, according to Rep. Chip Roy (R-Texas).
Roy is among the members of the far-right House Freedom Caucus who fought for starting the requirements sooner. He’s also a member of the House Rules Committee, which started debating the budget reconciliation bill at 1 a.m. At publication time, committee members were still working through the 537 amendments that were submitted. The Rules Committee is the last stop before a House vote, and Speaker Mike Johnson (R-La.) aims to pass the bill before the end of the week. 
Ans in a related story:
‘Don’t ‘f— with Medicaid,’ Trump tells GOP lawmakers: Several Republican lawmakers had pushed for deeper cuts to Medicaid, which has become a key sticking point in negotiations as fiscal conservatives seek cuts to help offset the bill’s tax provisions, according to the report. The bill also faces pushback from centrist Republicans in high-tax states like New York and California, who are advocating for changes to the $30,000 cap on state and local tax deductions.
“I think it was a meeting of love,” President Trump said, according to the report. “And there were a couple of things we talked about specifically where some people felt a little bit one way or the other. Not a big deal.” 

About the public’s health

Diseases are spreading. The CDC isn't warning the public like it was months ago: Many of the CDC's newsletters have stopped being distributed, workers at the CDC say. Health alerts about disease outbreaks, previously sent to health professionals subscribed to the CDC's Health Alert Network, haven't been dispatched since March. The agency's main social media channels have come under new ownership of the Department of Health and Human Services, emails reviewed by NPR show, and most have gone more than a month without posting their own new content. 

Poll: 83% of Americans say benefits of MMR vaccines outweigh risks: A new Annenberg Poll shows that 87% of Americans say the benefit of childhood measles, mumps, and rubella (MMR) vaccination outweighs the risk, and 67% say they know that MMR vaccines don't cause autism.

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About health insurance/insurers

Massive Medicaid cuts would ripple through nonprofit sector, too Great summary of the topic, including the effect on Easter Seals.

Veterans' VA Referrals to Private Medical Care Will No Longer Require Additional Doctor Review: The Department of Veterans Affairs has changed its process for veterans to get medical care from non-VA providers, removing a requirement that a referral to community care be reviewed by another VA doctor.
The VA announced Monday that it is enacting a provision of the Senator Elizabeth Dole 21st Century Veterans Healthcare and Benefits Improvement Act that will help ease veterans' access to medical services from private providers. 

About pharma

HHS sets ‘pricing targets’ to lower US drug costs: HHS is taking “immediate steps” to implement President Donald Trump’s executive order, Delivering Most-Favored-Nation Prescription Drug Pricing to American Patients — a key initiative aimed at reducing healthcare costs…
Under the executive order, HHS has until June 11 to develop and communicate drug pricing reduction goals with pharmaceutical manufacturers. If meaningful progress is not made, the department is instructed to begin the rulemaking process to enforce most-favored-nation pricing. However, the order does not outline a clear legal mechanism for mandating lower drug prices, and it remains uncertain how the directive would intersect with ongoing Medicare drug price negotiation efforts under the Inflation Reduction Act. 

Pfizer pays $1.25B upfront for rights to PD-1/VEGF bispecific from China's 3SBio: Top Story: Pfizer signed a licensing deal potentially worth over $6 billion with 3SBio, securing ex-China rights to the latter’s PD-1/VEGF-targeting bispecific antibody SSGJ-707 in oncology indications. The agreement — which includes an upfront payment of $1.25 billion — marks Pfizer's second recent move into the PD-1/VEGF bispecific antibody space.

About the public’s health

Kennedy’s placebo requirement for vaccine testing could cost lives:Robert F. Kennedy Jr. in his hearing before Congress last week doubled down on his plans to revamp the vaccine approval process. The health and human services secretary claimed that no vaccines other than the coronavirus shots had been tested against a placebo, which he vowed to “remedy.” An HHS spokesperson previously characterized conducting placebo-controlled trials as “a radical departure from past practices.”
These statements are flat-out wrong. Many vaccines are, in fact, tested against placebos. Those that aren’t always have a specific ethical and scientific rationale. Changing existing practice won’t make immunizations safer, but it will delay access and impede disease prevention.
Other related articles:
An Evidence-Based Approach to Covid-19 Vaccination and
FDA will limit Covid vaccines to people over 65 or at high risk of serious illness, leaders say

Nebraska to ban soda and energy drinks from SNAP under first USDA waiver: Nebraska is the first state to receive a federal waiver to ban the purchase of soda and energy drinks under the benefit program for low-income Americans long known as food stamps.
The move, announced Monday by U.S. Agriculture Secretary Brooke Rollins, would affect about 152,000 people in Nebraska enrolled in the Supplemental Nutrition Assistance Program, or SNAP, which helps families pay for groceries.
“There’s absolutely zero reason for taxpayers to be subsidizing purchases of soda and energy drinks,” Nebraska Gov. Jim Pillen said in a statement. “SNAP is about helping families in need get healthy food into their diets, but there’s nothing nutritious about the junk we’re removing with today’s waiver.”
Six other states — Arkansas, Colorado, Kansas, Indiana, Iowa and West Virginia — have also submitted requests for waivers banning certain foods and drinks or, in some cases, expanding access to hot foods for participants, according to the USDA.

World Health Assembly adopts historic Pandemic Agreement to make the world more equitable and safer from future pandemics: The WHO Pandemic Agreement sets out the principles, approaches and tools for better international coordination across a range of areas, in order to strengthen the global health architecture for pandemic prevention, preparedness and response. This includes through the equitable and timely access to vaccines, therapeutics and diagnostics. 

About healthcare personnel

Private funder HHMI pauses postdoc fellowship : The Hanna Gray fellowship, created by the Howard Hughes Medical Institute, supports postdoctoral researchers from diverse backgrounds in their transition to heading their own labs. During normal times, the opportunity was transformative, but in an era of cuts to research funding and uncertainty at universities, some saw it as a lifeline to an academic career…
HHMI, the largest private funder of biomedical research, announced it would no longer be considering applications for the upcoming cycle. It’s the latest retrenchment by HHMI, which had become a leader in efforts to make the science workforce more diverse, amid the Trump administration’s attacks on diversity, equity, and inclusion programs. 

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In other news:

America’s sickness economy An excellent review with useful charts.

Survey Highlights Progress, Persistent Barriers on Value-Based Care Journey: NAACOS, the National Association of ACOs, and Innovaccer, a company that has developed an interoperability platform for value-based care (VBC), have released a survey of healthcare professionals about their progress on value-based care transformation.
Here are some bullet-point highlights: 
• 30% of organizations reported that 25% or more of their revenue is tied to VBC contracts.
• More than 60% of organizations have increased their participation in VBC programs.
• Nearly 20% of organizations report that over half of their revenue comes from fully capitated or downside risk contracts.
• Barriers to adoption cited by respondents include financial risk, provider resistance, lack of data interoperability and the cost of technology to facilitate VBC.
• Those surveyed cited greater financial support, improved data sharing capabilities with payers and clearer regulatory guidelines as factors that would greatly support VBC adoption.

Trump’s DOJ Accuses Medicare Advantage Insurers of Paying ‘Kickbacks’ for Primo Customers I wrote about this suit before but this article is a nice summary of the issue.

As Congress Debates Cutting Medicaid, a Major Study Shows It Saves Lives: Poor adults who gained Medicaid coverage after the Affordable Care Act expanded access were 21 percent less likely to die during a given year than those not enrolled, the research shows. By analyzing federal records on 37 million Americans, two economists found that deaths fell not only among older enrollees but also among those in their 20s and 30s — a group often assumed to have few medical needs, and who would have been far less likely to qualify for Medicaid before the expansion.
The findings were published this month in a National Bureau of Economic Research working paper

About health insurance/insurers

Study suggests upcoding practices are fairly common across outpatient care: The report, compiled by researchers at Trilliant Health, found that the share of visits that were coded at higher intensities grew in emergency care, urgent care and physician office visits between 2018 and 2023. For example, the number of emergency department visits coded as 99284, or level four of five total, grew from 32.5% to 39.6% in the study window. 

About pharma

GLP-1s may cut risk of obesity-related cancers: 3 study notes: A new study has found GLP-1s may reduce the risk of developing obesity-related cancers by 41% compared to bariatric surgery — a benefit researchers believe could be tied to the drugs’ ability to reduce inflammation.  

White House, Cost Plus Drugs’ new drug manufacturing alliance: 5 notes: The White House has launched a new program focused on leveraging technology and private sector partnerships to find new ways to quickly produce key pharmaceutical ingredients and finished drugs at the point-of-care. 
The initiative, called Equip-A-Pharma, involves collaborations with Mark Cuban’s Cost Plus Drugs and three other healthcare partners. 

Regeneron to buy 23andMe out of bankruptcy for $256 million: Regeneron Pharmaceuticals said Monday it had entered into an agreement to buy the consumer genetics firm 23andMe out of bankruptcy for $256 million. The deal is subject to bankruptcy court and regulatory approvals.
The Tarrytown, N.Y.-based biotech said it would continue 23andMe’s consumer business and use the data the company has collected for drug development.

CVS, Walgreens bid for Rite Aid pharmacy assets: CVS Health Corp. is trying to buy stores and patient data from Rite Aid Corp., the beleaguered pharmacy chain that is going out of business after filing for bankruptcy a second time earlier this month….
Rite Aid has also received multiple bids on some of its pharmacy assets, such as patient data and inventory, from Walgreens Boots Alliance Inc., Albertsons Cos., Kroger Co., Giant Eagle Inc. and others, Rite Aid Chief Executive Officer Matthew Schroeder told employees…

HHS must preapprove pharma's proposed 340B rebate models, judge rules: Several big pharmas attempting to introduce a rebate model under the 340B programme, rather than offering an upfront discount on medicines, were hit with a setback Friday after a US district judge rejected lawsuits from several drugmakers. 
Bristol Myers Squibb, Eli Lilly and Johnson & Johnson had each filed suit last year after the US Health Resources and Services Administration (HRSA) rejected proposals from the drugmakers that would change how they deliver reduced-cost drugs to hospitals and clinics that serve uninsured and low-income patients…Judge Dabney Friedrich ruled on Friday that HHS has the authority to approve or reject the proposed rebate models, blocking the pharmas from moving forward with their 340B plans until they receive an explicit OK from Secretary Robert F. Kennedy. 
Per a notice filed earlier this month in the US District Court for the District of Columbia, HHS said it will be "in a position to provide guidance" about the proposed rebate models by the end of May.

About healthcare IT

Top 20 global cities for EHR interoperability FYI.
Also, according to the report conducted in March and April 2025:
• 88% of healthcare organizations outside the U.S. now prioritize regional software providers due to improved localization and faster compliance with local regulations.
• User satisfaction rates for regional EHR solutions reached an average of 91%, compared to a
declining rate of 68% for U.S.-based systems.
• 79% of international healthcare leaders report political and digital sovereignty considerations
influencing vendor selections, reflecting heightened awareness and sensitivity towards national data control and security.
• Over 84% of surveyed respondents identified regional vendors as providing superior customization and adaptability to specific local clinical workflows.
• Implementation timelines for regional vendors are on average 40% shorter than those of major U.S.-based EHR providers, enhancing their attractiveness in dynamic healthcare environments.
• Cost transparency and predictable pricing structures from regional vendors achieved an approval rate of 82%, contrasting sharply with 47% satisfaction for major U.S.-based competitors.

Today's News and Commentary

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In other news:  

About hospitals and healthcare systems

63 health systems ranked by annual revenue  FYI 

About the public’s health

The Domestic Consequences of Defunding Global Health A really good summary of the issue.
In a related article: WHO: 70% of Countries Already Face Health Disruptions Amid Aid Cuts 

About healthcare IT

276 Million Patient Records Compromised — What You Need To Know: A May 5 HIPPA Journal report has confirmed that in 2024 healthcare attacks resulted in a staggering “276 million breached records.” Now, a May 13 Check Point report has warned that the hackers behind a newly-identified and healthcare-focused attack are looking to steal even more sensitive employee and consumer data.  

About health technology

FDA endorses first-of-its-kind blood test for Alzheimer’s disease: The test, called Lumipulse, measures two proteins found in the blood’s plasma to determine whether a patient has amyloid plaques in the brain. Up until now, physicians have mostly used costly, more invasive tests that involve puncturing the lumbar — known as a spinal tap — and brain scans that expose patients to radiation to confirm the presence of amyloid. The Lumipulse test takes a simple blood draw. 

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About health insurance/insurers

UnitedHealth Group Is Under Criminal Investigation for Possible Medicare Fraud: While the exact nature of the potential criminal allegations against UnitedHealth is unclear, the people said the federal investigation is focusing on the company’s Medicare Advantage business practices.

About hospitals and healthcare systems

Hospital expenses per inpatient day across 50 states FYI

About the public’s health

FDA to remove ingestible fluoride prescriptions for children from the market: 7 notes: The FDA plans to begin removing ingestible fluoride prescription drug products for children from the market later this year.
 Comment: Excessive fluoride can cause all the harms JFK, Jr claims; but, most water supplies have levels that are beneficial. Further, infants who are breast fed need supplements. Science loses again.

RFK Jr. says people should not take medical advice from him, defends HHS cuts during congressional hearings Yes, but they DO listen when he issues harmful and incorrect medical statements.

How Chronic Disease Became the Biggest Scourge in American Health A great comparison (in charts) of US healthcare versus other countries.

About healthcare IT

88% of breached patient records since 2010 tied to hacking: Study: From October 2009 to October 2024, ransomware and hacking have increasingly driven healthcare data breaches, a May 14 study published in JAMA Network Open found. 
The study examined ransomware attacks and other hacking incidents across all healthcare organizations covered by HIPAA from October 2009 through October 2024. It analyzed breaches affecting 500 or more patient records that were reported to the U.S. Department of Health and Human Services (HHS) Office for Civil Rights.

About health technology

Baby Is Healed With World’s First Personalized Gene-Editing Treatment: The baby, now 9 ½ months old, became the first patient of any age to have a custom gene-editing treatment, according to his doctors. He received an infusion made just for him and designed to fix his precise mutation.
The investigators who led the effort to save KJ are presenting their work on Thursday at the annual meeting of the American Society of Cell & Gene Therapy, and are also publishing it in the New England Journal of Medicine. 

Today's News and Commentary

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About health insurance/insurers

CBO: GOP Medicaid plan would make 7.6 million people uninsured: The Medicaid portion of the House GOP’s massive domestic policy bill would result in 10.3 million people losing Medicaid coverage by 2034 and 7.6 million people going uninsured, according to a partial (CBO) Congressional Budget Office estimate. 

CMS proposes including Part B drugs in Medicare price negotiations: 5 key updates: CMS has proposed including select Medicare Part B drugs in the third round of its drug price negotiation program, according to draft guidance released May 12. 
The agency said the proposal is designed to enhance transparency, focus on high-expenditure drugs and ensure that efforts to establish fair pricing do not stifle pharmaceutical innovation.
Comment: Recall drug negotiations have been about Part D drugs.

Expect More Downside Risk in Medicare's Payment Models, CMS Official Says: Physicians should expect to see more Medicare alternative payment models that involve downside risk, Abe Sutton, JD, director of the Center for Medicare and Medicaid Innovation (CMMI), said Tuesday.
"We've found at the innovation center that when we have 'upside-only' payment models, there's not necessarily an incentive ... for participants to change how they engage in care delivery," Sutton said… 
Also on Tuesday, Sutton outlined a new approachopens in a new tab or window that CMMI is taking to its work, focused on three "pillars":
Promote evidence-based prevention
Empower people to achieve their health goals.
Drive choice and competition.

About hospitals and healthcare systems

Recognizing Outstanding Care: Healthgrades Announces 2025 Top Hospitals for
Patient Experience
 
: FYI

About pharma

AbbVie paying $355M, potentially billions more, in deal for new RNA tech:AbbVie is entering a collaboration and license option deal with ADARx Pharmaceuticals to develop a new type of RNA technology for disease areas like neuroscience, immunology and oncology.
The deal could net San Diego-based ADARx several billion dollars in payments, if successful.
Late clinical-stage biotech ADARx is working on small interfering RNA, or siRNA, therapeutics, a class of molecules capable of regulating gene expression and protein production.

About the public’s health

EPA will weaken rule curbing forever chemicals in drinking water: The Environmental Protection Agency announced Wednesday that it plans to rescind and reconsider limits on four “forever chemicals” under a landmark drinking water standard implemented last year by President Joe Biden.

US Children Living With a Parent With Substance Use Disorder: Nearly 19 million children were estimated to be living in a household with at least 1 parent with SUD, accounting for one-quarter of all US children in 2023. Children in such households are more likely to develop adverse health outcomes than their peers without exposure to parental SUD.

Increased sedentary behavior is associated with neurodegeneration and worse cognition in older adults over a 7-year period despite high levels of physical activity: Highlights

  • Greater sedentary behavior is related to neurodegeneration and worse cognition.

  • Associations differed by APOE-ε4 carrier status in cross-sectional models.

  • Sedentary behavior is an independent risk factor for Alzheimer's disease. 

 

About healthcare IT

A decade of AI rules on ice?: The proposed bill prohibits state and local governments from enforcing “any law or regulation regulating artificial intelligence models, artificial intelligence systems, or automated decision systems during the 10-year period beginning on the date of the enactment of this Act.”  

About healthcare personnel

The World Is Wooing U.S. Researchers Shunned by Trump: For examples:
—Last week, at the urging of more than a dozen members, the European Union announced it would spend an additional 500 million euros, or $556 million, over the next two years to “make Europe a magnet for researchers.”
—Of 1,600 people who responded to a March poll in the journal Nature — many of them Ph.D. or postdoctoral students in the United States — three out of four said they were considering leaving the country because of the Trump administration’s policies. 

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House Republicans unveil Medicaid cuts that Democrats warn will leave millions without care: A good short summary.

What Are the Projected 2025 Health Plan Cost Trends?: Key health plan cost trend survey findings
In addition to the double-digit projected prescription drug trend noted above, key survey findings about the coming year’s trend projections include:

  • Survey respondents project the per-person cost trend for PPO/POS plans to be 7.9 percent.

  • Projected specialty drug trend is 13.3 percent. Drivers of projected specialty drug trend are primarily due to the utilization of new high-cost specialty drugs, replacing lower-cost therapies. Trend attributable to utilization is forecast to be 7.8 percent, accounting for almost 60 percent of the specialty drug gross cost trend increase before rebates.

  • Unit cost, including factors like price inflation, is still the primary driver for inpatient hospital trends.

  • Plan sponsor focus has shifted dramatically to cost- and quality-management strategies related to prescription drugs and weight loss-treatments specifically, which now account for four of the top five cost-management strategies.

  • Trend projections for dental provider organizations are 4.5 percent.

  • Projected vision trend is 3.0 percent for reasonable and customary plans.

  • While the projected medical trend for Medicare-eligible retirees with Medicare Advantage PPO plans is 4.9 percent, the projected Medicare Part D trend is 8.9 percent.  

About pharma

Trump signs executive order seeking to lower US drug costs by challenging prices in other countries: President Donald Trump signed a sweeping executive order Monday morning that promises to crack down on “unreasonable or discriminatory” practices by foreign countries that result in Americans paying far higher costs for prescription drugs.
Also, drugmakers must start offering US patients the lowest price paid for a drug in a peer country, known as the “Most Favored Nation” price, or face consequences, the president said. He directed the Department of Health and Human Services to come up with price targets within 30 days.

About the public’s health

FDA Approves First At-Home Cervical Cancer Test: On Friday, a San Francisco-based startup received FDA approval for the first-ever at-home cervical cancer test.
The company, named Teal Health, was founded in 2020 and has raised $23 million. The startup has developed an at-home cervical cancer screening kit, which seeks to give patients an alternative to the in-office pap smear. 

Today's News and Commentary

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Judge Asks DOJ To Define DEI In Health Grant Case: A Massachusetts federal judge on Thursday ordered U.S. Department of Justice lawyers to provide the Trump administration's definitions of diversity, equity and inclusion, saying he needs to know so he can consider whether that is a valid basis for pausing federal health research…

Why a Planned Reorganization of the FDA Creates Major Challenges: An insightful piece by two former FDA heads.

About health insurance/insurers

Toward Integrating Care for Dually Eligible Beneficiaries: FYI. A thoughtful analysis and suggestions for those receiving healthcare through Medicare and Medicaid.

About hospitals and healthcare systems

The week in health system M&A: 2 deals close, another called off: FYI

About pharma

Appeals court rejects AstraZeneca's challenge to Medicare drug price talks: AstraZeneca's bid to derail Medicare's power to negotiate lower drug prices on certain prescription drugs under the Inflation Reduction Act (IRA) has failed in a US appeals court.In a ruling Thursday, the Third Circuit Court of Appeals sided with the US government, affirming a lower court's 2024 dismissal of AstraZeneca's lawsuit. That court found AstraZeneca hasn't shown it was directly harmed by the negotiation programme and failed to prove the law violated its constitutional rights.

About the public’s health

Rising food prices in US getting in way of healthy eating, survey of Americans finds: American adults say sticker shock at the grocery store is making it harder for them to have a healthy diet, according to a nationally representative survey of adults by the Pew Research Center, a nonpartisan fact tank that conducts data-driven research.
Ninety percent of adults in the United States say the price of healthy food has risen over the past few years, and over two-thirds (69%) say higher food prices are making it difficult to eat a healthy diet. 

Effectiveness and Safety of Respiratory Syncytial Virus Vaccine for US Adults Aged 60 Years or Older: Findings  In this case-control study of 787 822 patients tested for RSV, vaccine effectiveness was approximately 75% among adults aged 60 years or older against RSV-associated acute respiratory infection, urgent care or emergency visits, or hospitalization; effectiveness was less but still substantial among immunocompromised patients. An estimated excess of 11.2 cases of Guillain-Barré syndrome followed administration per 1 000 000 doses of RSV vaccine.
Meaning  These findings suggest that RSV vaccination of older patients is effective even for most immunocompromised patients, but diagnoses of Guillain-Barré syndrome are increased after vaccination.

About healthcare IT

FaceAge, a deep learning system to estimate biological age from face photographs to improve prognostication: a model development and validation study : Our results suggest that a deep learning model can estimate biological age from face photographs and thereby enhance survival prediction in patients with cancer. Further research, including validation in larger cohorts, is needed to verify these findings in patients with cancer and to establish whether the findings extend to patients with other diseases. Subject to further testing and validation, approaches such as FaceAge could be used to translate a patient’s visual appearance into objective, quantitative, and clinically valuable measures. 

About healthcare personnel

TIME Reveals the 2025 TIME100 Health List of the World’s Most Influential People in Health: FYI

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In other news:

Characterization of Research Grant Terminations at the National Institutes of Health: Targeted grant terminations have affected more than $1.8 billion in NIH funding. Terminations were spread across nearly all NIH institutes and centers, although cuts disproportionately impacted the NIMHD (30% of all funding).
The proportion of terminated grant funding was higher than the proportion of grants terminated across most institutes and centers, suggesting that larger-than-average grants were more likely to be terminated. Although most terminated grants were classified as independent research projects, 20% were formal training, fellowship, or career development awards. Study findings also demonstrate that grant terminations have affected both public and private recipient institutions across the US.  

About pharma

Teva to cut nearly 3000 jobs as shift from pure-play generics picks up pace: Teva plans to cut 8% of its workforce as part of efforts to trim $700 million in costs and achieve its target of reaching a 30% operating profit margin by 2027. The move means that the company's workforce of just over 36,000 will be slashed by around 2900 positions. 

About the public’s health

Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults ≥50 Years:  In this phase 3 study, mRNA-1083 elicited noninferior immune responses against standard care immunization: licensed standard-dose or high-dose seasonal influenza vaccine (A/H1N1, A/H3N2, B/Victoria, B/Yamagata) coadministered with licensed SARS-CoV-2 (Omicron XBB.1.5) vaccine. The multicomponent vaccine mRNA-1083 had an acceptable tolerability and safety profile.   

About healthcare personnel

Physician Flash Report: Key Takeaways
Two out of five providers in physician practices are advanced practice providers (APPs). The gap between APPs and physicians continues to close and is driven primarily by surgical and primary care.
Subsidies for surgical specialties continue to grow. Physician practices must carefully consider site of service, which impacts revenue and margin.
Provider compensation is growing slowly. Physician practices should consider retention strategies to keep talent in today’s highly competitive marketplace for physicians and clinicians. 

Today's News and Commentary

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Health Care (From U.S.News Best State Rankings): FYI

About hospitals and healthcare systems

Hospital Price Transparency in Action: An Analysis of Radiology Procedure Price Variation in Children's Hospitals Between 2023 and 2024: Findings show a statistically significant decrease in price variation, with the coefficient of variation (CV) for negotiated rates declining by 19.2% but overall prices continuing to rise, with payer specific negotiated rates increasing by an average 6.7%. Price transparency policies may contribute to reduced price dispersion; however, the average price did increase.

Monthly Healthcare Industry Financial Benchmarks: Highlights from the March 2025 data include: 

  • Operating margins for U.S. health systems narrowed slightly to 0.9% in March, after holding steady at 1% for both January and February, while hospital operating margins rose year-over-year (YOY). 

  • Non-labor expenses continued to rise faster than other expense categories, due in part to double-digit increases in both drug and supply expenses versus the same month last year. 

  • Patient demand was up nationwide across most metrics in March, following decreases in February, as growth in outpatient visits outpaced inpatient admissions.  

  • Gross outpatient revenues led overall hospital revenue increases, jumping 10.0% YOY as hospitals and health systems continue to see care shift from inpatient to outpatient settings.  

  • Per-physician expenses rose to $1.2 million in the first quarter, representing an increase of 3% compared to Q4 2024 and 10.3% versus Q1 2024. 

Northwell, Nuvance's 28-hospital merger crosses the finish line: As expected, Northwell Health and Nuvance Health have consummated their 28-hospital merger.
The resulting nonprofit juggernaut delivers care to more than 13 million people in New York and Connecticut by way of a $22.6 billion operating budget. It employs more than 104,000 people, and alongside the hospitals runs over 1,050 ambulatory care sites, 73 urgent care locations and three medical research and education organizations.  

About pharma

The 25 priciest drug classes for hospitals FYI. By far, the largest class is Antineoplastic targeted agents: $7.3 billion.

About the public’s health

FDA label updates aim to make it easier to choose healthy foods: FDA updates to criteria for using the term “healthy” on manufactured and packaged foods are aimed at helping consumers quickly and easily identify what they need to eat for a healthful diet, experts said during an FDA webinar
The FDA released the final rule updating the definition of the nutrient content claim “healthy” for manufactured and packaged foods in December 2024.   

About healthcare IT

Mercer launches tool that allows employers to predict healthcare costs linked to climate events: Climate-related health challenges are driving up employer spending, and a new tool built by Mercer aims to help firms anticipate the potential costs.
The Climate Health Cost Forecaster was developed in partnership with the National Commission on Climate and Workforce Health. It seeks to arm employers with the data necessary to estimate the long-term health costs tied to weather events like extreme heat, poor air quality, flooding and hurricanes.
The tool is designed to offer companies a local perspective on the vulnerabilities that could impact their workforces. It leans on a combination of Mercer's proprietary models for healthcare costs and key weather and epidemiological research, according to an announcement. 

Today's News and Commentary

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In other news:

5 Places to Turn for Accurate Health Information In view of the federal government’s cutbacks on information, this article is a good source of other sources you can use.

About pharma

Trump signs order to boost domestic drug manufacturing as pharma tariffs loom: The order directs the Food and Drug Administration to reduce the amount of time it takes to approve manufacturing plants in the U.S. by eliminating unnecessary requirements, streamlining reviews and working with domestic drugmakers to “provide early support before facilities come online,” according to a White House fact sheet.
It also directs the agency to raise inspection fees for foreign manufacturing plants, improve the enforcement of active-ingredient source reporting by overseas producers and consider publicly listing facilities that don’t comply.

About healthcare IT

Parental Technology Use in a Child’s Presence and Health and Development in the Early Years: This systematic review and meta-analysis found that parental technology use in their child’s presence was significantly associated with poorer cognition and prosocial behavior, lower attachment, higher levels of internalizing and externalizing problems, and higher levels of screen time. 

Today's News and Commentary

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In other news:

Postdischarge contact within 7 d does not reduce use of acute care at 30 d: In adults, PDC interventions delivered by nonclinician providers within 7 days of hospital discharge do not reduce use of acute care at 30 days.
Comment: Many health plans use the metric of contact within 7 days of discharge to calculate quality bonuses.

Trump’s 2026 budget plan cuts healthcare funds: 6 notes FYI- a good update.

About Covid-19

UVA research finds distinct changes in immune systems of COVID-19 survivors: New groundbreaking research from the University of Virginia's School of Medicine has revealed that the immune systems of COVID-19 survivors, specifically those with breathing issues, have distinct changes.
According to a release from the university, officials say these findings shed light on the complexity of Long COVID and may pave the way for more personalized and effective treatments. 

About health insurance/insurers

IRS unveils new HSA limits for 2026. Here’s what investors need to know FYI

Medicaid cuts, mortality, and health-care expenditure in the USA: Based on projected coverage losses, we estimate that approximately 623 000 additional individuals aged 25–64 years (95% CI 91 000 to 1·07 million) will face catastrophic health-care costs annually. 

Payers ranked by Q1 profits FYI

Estimating the Budgetary Impact of Reforms to the Medicare Advantage Quality Bonus Program: Reforms to the Medicare Advantage QBP could save the federal government $2.6 billion to $14.1 billion in 2026. The impact of reforms varies considerably over contract characteristics due to differences in quality and the geographic location of contracts. These estimates are consistent with other research about QBP spending.

About hospitals and healthcare systems

Hospital Capital Expenditures Associated With Prices And Hospital Expansion Or Withering, 2010–19:  This study investigated the market dynamics linking hospital capital expenditures during the period 2010–19 to changes in volume, market share, and prices. We found that hospitals investing more in capital gained market share and raised prices, whereas hospitals investing relatively less in capital lost market share and increased prices less. Taken together, these forces perpetuate a cycle of expanding and withering hospitals. Study findings suggest important limits to antitrust as a mechanism to address high and rising prices, and the findings could inform policies to forestall or eliminate the financial decline of withering hospitals, thereby preserving access and promoting competition.

Hospitals Acquired By Private Equity Firms: Increased Postoperative Mortality For Common Inpatient Surgeries: We found that PE acquisition was associated with a 2.7-percentage-point increase in thirty-day postoperative mortality compared with control hospitals, driven primarily by an increase in failure to rescue (3.9 percentage points), with no observed change in the rate of complications. Subset analysis revealed that the increase in mortality was particularly pronounced for unplanned (emergent) surgeries, whereas no significant changes were observed for planned (elective) surgeries. Our findings suggest that PE acquisition may adversely affect the management of emergent surgical cases, raising critical considerations for policy makers and health care stakeholders regarding the influence of PE ownership on patient safety.

About pharma

FDA probes compounding pharmacies over quality concerns: The FDA plans to gather information from 250 compounding outsourcing pharmacies amid safety and quality concerns. 
In a May 1 notice, the agency said it will survey outsourcing facilities about challenges and opportunities related to market and business viability, compliance, quality production and interactions with the FDA.  

About healthcare personnel

Europe unveils $565 million package to retain scientists, and attract new ones: The European Commission on Monday unveiled a roughly $565 million package to retain and attract scientists, as other countries try to leverage the Trump administration’s dismantling of research programs in the U.S. to build up their own enterprises. 
The funding program, amounting to 500 million euros, is designed to make “Europe a magnet for researchers,” Ursula von der Leyen, the president of the commission, said at an event at Paris’ Sorbonne University called “Choose Europe for Science.” Appearing along with French President Emmanuel Macron, von der Leyen said the funding, which will last through 2027, would support researchers from Europe and around the world. 

Pathways To Primary Care: Charting Trajectories From Medical School Graduation Through Specialty Training: Among 353,590 physicians who graduated during the period 2001–15, 11.8 percent pursued initial training in family medicine, 33.5 percent training in internal medicine, and 10.5 percent training in pediatrics. Primary care yield, defined as the percentage of physicians who complete their initial postgraduate training in a primary care specialty and conclude their training in any primary care specialty, was 97.0 percent for family medicine, 35.5 percent for internal medicine, and 54.4 percent for pediatrics. After internal medicine and pediatrics residencies, large percentages of physicians left primary care to train in subspecialties and other fields. Further research must document how many physicians enter careers in primary care practice.

About healthcare finance

Deerfield raises $600M healthcare fund to invest in therapeutics, AI:Deerfield Management closed its third Healthcare Innovations Fund on Monday, raising $600 million to invest in therapeutics and care delivery technologies, as well as machine learning and AI. 
The latest close comes about five years after Deerfield's last raise in 2020, when it clinched $840 million to fund healthtech innovations and novel treatments. 

Today's News and Commentary

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In other news:

Trump’s budget proposes steep cuts to NIH, health funding: The 2026 proposal is seeking to cut $33.3 billion in discretionary funding for HHS, representing a 26.2 percent reduction compared to the fiscal 2025 budget.
This includes a $3.6 billion reduction in discretionary funding for the Centers for Disease Control and Prevention (CDC), an $18 billion reduction for the National Institutes of Health (NIH), a $674 million reduction for the Centers for Medicare and Medicaid Services (CMS) Program Management and a $240 million reduction for Administration for Strategic Preparedness and Response (ASPR) Hospital Preparedness Program.
The only health program that gains discretionary funding in the proposal is HHS Secretary Robert F. Kennedy Jr.’s Make America Healthy Again(MAHA) Commission, for which the budget provides $500 million. 

About health insurance/insurers

CMS sets up real-time medical fraud center with DOGE; Federal contractor rolls out commercial tool: The Centers for Medicare & Medicaid Services (CMS) has launched the Fraud Detection Operation Center (FDOC) to fight waste, fraud and abuse, the agency announced this week.
Comment: This task had been done by the Inspector General; it is not new or innnovative.

DOJ sues major insurers, brokers over alleged Medicare Advantage kickbacks:The Department of Justice has filed a sweeping lawsuit against Humana, Aetna, and Anthem, along with Medicare Advantage brokers eHealth, GoHealth, and SelectQuote, alleging a multi-year scheme involving unlawful kickbacks and discriminatory practices against disabled MA enrollees.
According to the May 1 complaint filed in the U.S. District Court for the District of Massachusetts, the insurers paid hundreds of millions of dollars from 2016 through at least 2021 to the brokers in exchange for preferential treatment, including steering enrollees toward their MA plans and away from competitors, regardless of the quality of the plans. The DOJ filed the lawsuit based on a whistleblower complaint initially filed by a former eHealth employee under the False Claims Act. 

About hospitals and healthcare systems

Understanding the Hospital Readmission Reduction Program FYI

About pharma

Lilly star weight-loss drug Zepbound faces coverage challenge from CVS Health: CVS Health said the drugs Wegovy and Saxenda from rival drugmaker Novo Nordisk will become the preferred options on its standard formulary, or list of covered drugs, as of July 1. Zepbound will be excluded. 

GLP-1s can help employers lower medical costs in 2 years, new study finds:
KEY POINTS

  • Aon researchers found that within two years, improved health outcomes for patients who were taking GLP-1 drugs lowers the growth rate of medical care costs.

  • Aon looked at medical claims data for 139,000 U.S.-based workers with employer health coverage who took GLP-1 medications between 2022 and 2024.

  • Since 2023, GLP-1s have driven up employer spending on drugs at a faster pace than high-priced specialty drugs used to treat cancer and autoimmune conditions, according to an Evernorth study.

About the public’s health

Diabetes deaths fall to lowest levels in years, in early CDC figures:There were 103,294 deaths from diabetes in 2021, up more than 17% from 87,647 deaths in 2019 before the pandemic. Provisional data reported so far for 2024 have tallied 94,294 diabetes deaths last year.